Portable ultra-low-field brain MRI: test-retest reliability and correspondence to high-field MRI
Motivation: Ultra-low-field MRI scanners offer a cost-effective and portable alternative to high-field neuroimaging. Goal(s): To quantify between-scanner test-retest reliability of 64mT brain scans, and their correspondence to 3T MRI. Approach: We scanned 23 healthy participants on two Hyperfine 64mT scanners and a GE 3T scanner using T1w and T2w scans at multiple resolutions. We segmented images into 98 structures and estimated their volumes. Results: We demonstrate excellent reliability of volumetric estimates from ultra-low-field MRI, and high correspondence to high-field scans. The highest reliability and high-field correspondence was obtained using T2w ultra-low-field scans, super-resolved by combining three orthogonal acquisitions with low through-plane resolution. Impact: Measures of brain volume from Hyperfine portable ultra-low-field MRI scans show excellent test-retest reliability across scanners, and excellent correspondence to similar estimates from high-field MRI. This enables quantitative analysis of cost-effective and portable neuroimaging in various contexts, including low-resource environments.
Authors
- Niall Bourke (ORCID: https://orcid.org/0000-0001-6478-1430)
- Robert Leech (ORCID: https://orcid.org/0000-0002-5801-6318)
- Paul Cawley (ORCID: https://orcid.org/0000-0002-4353-0656)
- Flavio Dell’Acqua (ORCID: https://orcid.org/0000-0001-5313-5476)
- Steven Williams (ORCID: https://orcid.org/0000-0003-4299-1941)
- Francesco Padormo (ORCID: https://orcid.org/0000-0001-5699-2692)
- Tomoki Arichi (ORCID: https://orcid.org/0000-0002-3550-1644)
- František Váša (ORCID: https://orcid.org/0000-0001-6744-7139)
- David J. Lythgoe (ORCID: https://orcid.org/0000-0002-5078-9025)
- Rosalyn Moran (ORCID: https://orcid.org/0000-0002-2736-2621)
- Ashwin Venkataraman (ORCID: https://orcid.org/0000-0001-7977-1948)
- Tobias Wood (ORCID: https://orcid.org/0000-0001-7640-5520)
- Sean Deoni (ORCID: https://orcid.org/0000-0002-0633-6328)
- Levente Baljer (ORCID: https://orcid.org/0009-0000-2298-9129)
- Carly Bennalick
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/2696
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00