Age-related assessment in a subset of SHIP data of intracranial vessel geometry from TOF MRI data

Motivation: Intracranial vessels undergo age-related changes with increased risk of vascular pathologies such as atherosclerosis, or intracranial aneurysms. The occurrence probability of these pathologies could be indicated based on an altered vascular geometry. Goal(s): The application of a geometric analysis to the vascular system of healthy volunteers of two age groups to study age-related changes in the geometry of intracranial arteries. Approach: The analysis involved labeled centerline determination of intracranial arteries and calculating geometric parameters. Results: Our study provided quantitative insights into age-related changes in intracranial artery geometry. Future research with larger, diverse samples can enhance the understanding and enable ML-based analyses. Impact: The objective was to examine age-related changes in women of intracranial arteries by performing a geometric analysis on healthy volunteers. The quantitative evaluation enhances the comprehension of how intracranial artery geometry evolves with age.