Estimating pathologic prognostic factors in epithelial ovarian cancers using apparent diffusion coefficients from functional tumour burden

Motivation: EOC is highly heterogeneous, meaning the average ADC value of the total tumor cannot reflect its internal components, which vary based on pathology. Goal(s): This study sought to assess the utility of ADC values from total and functional tumor burdens to determine pathologic prognostic factors in EOC. Approach: Using k-means clustering to divide the tumor into 2 clusters based on their ADC values, the low ADC cluster was considered to be high cellular. Furthermore, minimum, maximum and average ADC values of functional tumor were calculated. Results: ADC values derived from functional tumor could be used to assess preoperative prognostic factors in EOC. Impact: ADC values derived from functional tumor could be used to assess preoperative prognostic factors in EOC.