Exploring Brain Microstructure with Ultra-high b-values Diffusion MRI: A NODDI Model Comparison
Motivation: The benefits of using ultra-high b-values diffusion MRI (b>6000s/mm2) on characterizing and resolving brain microstructure are still unclear. Goal(s): To determine if the NODDI metrics computed from ultra-high b-values can help characterizing and providing more biological information related to brain microstructure. Approach: NODDI metrics are compared between different b-schemes, and between the corpus callosum and hippocampal subfields. Results: NODDI metrics computed with ultra-high b-value data can help characterize different subfields. Higher NDI and ODI differences in the corpus callosum and hippocampal subfields are observed with larger b-values. Impact: We show that NODDI models can work with ultra-high b-values and help characterizing and providing more biological information related to brain microstructure.
Authors
- Junye Yao (ORCID: https://orcid.org/0000-0002-8633-8744)
- Paween Wongkornchaovalit (ORCID: https://orcid.org/0000-0001-5540-2363)
- Jianhui Zhong (ORCID: https://orcid.org/0000-0002-8887-8103)
- Hongjian He (ORCID: https://orcid.org/0000-0001-6272-0810)
- Bo Dong (ORCID: https://orcid.org/0000-0003-3201-846X)
- Hui Zhang (ORCID: https://orcid.org/0000-0003-1520-2433)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/5113
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00