Hemodynamic analysis of non-stenotic middle cerebral artery in patients with cerebral ischemia based on 4D Flow MRI

Motivation: The change of hemodynamics in patients with symptomatic cerebral ischemia are not clear. Goal(s): This study aims to explore the difference of hemodynamic characteristics in non-stenotic middle cerebral artery (MCA) between healthy subjects and cerebral ischemia patients. Approach: The multiple hemodynamic parameters in the proximal, curved and distal segments of MCA were quantitatively analyzed in these two groups by using 4D flow MRI. Results: The results showed that the peak blood flow velocity was lower and the circumferential WSS reduced in MCA, the energy loss impaired in the M1 segment of MCA when compared cerebral ischemia patients with healthy subjects. Impact: This study was based on 4D flow MRI to explore the hemodynamic characteristics of cerebral ischemia in non-stenosis MCA, which is helpful to reveal the mechanism of cryptogenic stroke and provides a possibility for future prediction of stroke risk.