The utility of diffusion kurtosis imaging in assessing immunoglobulin G4-related kidney disease: a feasibility study
Motivation: Clinical diagnosis and assessment of immunoglobulin G4 (IgG4)-related disease is difficult. We explored whether diffusion kurtosis imaging (DKI) can resolve this difficulty. Goal(s): To explore the feasibility of using DKI in the assessment of IgG4-related kidney disease (IgG4-RKD)Approach: We measured the apparent diffusion coefficient (ADC) and DKI-derived parameters of the renal parenchyma, cortex, and medulla, then analyzed correlations between quantitative image parameters and clinical indicators. Results: DKI-derived quantitative parameters were correlated with clinical indicators and demonstrated feasibility in the assessment of IgG4-RKD. Impact: The DKI technique can help to detect IgG4-RKD lesions. DKI-derived quantitative parameters can assess IgG4-RKD clinical activity and facilitate evaluation of IgG4-RKD prognosis.
Authors
- Jinxia Zhu
- Alto Stemmer (ORCID: https://orcid.org/0000-0002-3016-3498)
- Ke Zheng (ORCID: https://orcid.org/0000-0002-4624-0881)
- Gumuyang Zhang
- Er‐Jia Guo (ORCID: https://orcid.org/0000-0001-5702-225X)
- Grimm Robert
- Hao Sun (ORCID: https://orcid.org/0000-0002-3670-2886)
- Jiahui Zhang
- Xuemei Li (ORCID: https://orcid.org/0000-0003-4334-2791)
- Zhengyu Jin (ORCID: https://orcid.org/0000-0003-4192-8991)
- Xiaoxiao Zhang (ORCID: https://orcid.org/0000-0003-3762-2287)
- Fei Teng (ORCID: https://orcid.org/0000-0002-8834-5067)
- Lixia Chen (ORCID: https://orcid.org/0000-0003-2196-1428)
- Xin Bai
- Lili Xu
- Qianyu Peng (ORCID: https://orcid.org/0009-0001-3930-1092)
- Zhuorui Xue
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/2588
- Primary Topic
- IgG4-Related and Inflammatory Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00