Exploring the Efficacy of Different Combinations of B-Values and B-Tensor Shapes in Assessing Spinal Cord in MS and NMOSD Using Micro-FA

Motivation: The necessity to accurately delineate microstructural changes in the spinal cords of MS and NMOSD patients in vivo. Goal(s): Assess if multiple b-tensor diffusion MRI data enhances the clinical utility of Micro Fractional Anisotropy (μFA) in distinguishing pathological variances in MS and NMOSD. Approach: Comparative analysis of μFA values derived from planar tensor encoding data (DDE) and a combination of DDE with linear tensor encoding data was conducted. Results: No significant μFA difference between MS and NMOSD was found, and additional linear tensor encoding data did not improve the results, highlighting the need for optimized imaging protocols. Impact: This study elucidates the criticality of optimizing imaging protocols over merely aggregating data for precise diagnostic outcomes in MS and NMOSD. It prompts further investigation into refining imaging methodologies to uncover microstructural changes, enhancing diagnostic accuracy and subsequent patient management.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/2513
Primary Topic
Medical Imaging and Analysis
Type
article
Field-Weighted Citation Impact
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article

Exploring the Efficacy of Different Combinations of B-Values and B-Tensor Shapes in Assessing Spinal Cord in MS and NMOSD Using Micro-FA

Julien Cohen‐Adad, Akifumi Hagiwara, Akihiko Wada, Kazumasa Yokoyama et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Medical Imaging and Analysis
article

Exploring the Efficacy of Different Combinations of B-Values and B-Tensor Shapes in Assessing Spinal Cord in MS and NMOSD Using Micro-FA

Julien Cohen‐Adad, Akifumi Hagiwara, Akihiko Wada, Kazumasa Yokoyama, Masaaki Hori, Issei Fukunaga, Christina Andica, Shohei Fujita, Katsuhiro Sano, Koji Kamagata, Shigeki Aoki, Kouhei Kamiya, Katsutoshi Murata
article en

Abstract

Motivation: The necessity to accurately delineate microstructural changes in the spinal cords of MS and NMOSD patients in vivo. Goal(s): Assess if multiple b-tensor diffusion MRI data enhances the clinical utility of Micro Fractional Anisotropy (μFA) in distinguishing pathological variances in MS and NMOSD. Approach: Comparative analysis of μFA values derived from planar tensor encoding data (DDE) and a combination of DDE with linear tensor encoding data was conducted. Results: No significant μFA difference between MS and NMOSD was found, and additional linear tensor encoding data did not improve the results, highlighting the need for optimized imaging protocols. Impact: This study elucidates the criticality of optimizing imaging protocols over merely aggregating data for precise diagnostic outcomes in MS and NMOSD. It prompts further investigation into refining imaging methodologies to uncover microstructural changes, enhancing diagnostic accuracy and subsequent patient management.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 80%
Medical Imaging and Analysis
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