Construction of a Hybrid Vaccine Based on Der f 35-Derived Peptides with Reduced Allergenicity
The designed B-cell epitope vaccine of Der f 35 showed greatly diminished allergenicity and Th2 activity. It could be an effective and safe candidate to prevent allergic adverse reactions during the immunotherapy of mite allergy and merits the further study.
Authors
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1034-0757)
- Qiaozhi Qin
- Xiang Chen (ORCID: https://orcid.org/0000-0002-1180-3891)
- Haoyang Hu (ORCID: https://orcid.org/0009-0001-8604-7277)
- Zhiqiang Xu
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Jiangsu Cancer Hospital (CN)
- Northern Jiangsu People's Hospital (CN)
- Jiangsu Province Hospital (CN)
- Second Affiliated Hospital of Nantong University
- Nanjing Medical University (CN)
Publication Details
- Journal
- International Archives of Allergy and Immunology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1159/000541815
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00