Evaluating and reporting LET and RBE-weighted dose in proton therapy for glioma – The Dutch approach
The study presents a harmonization of approaches to evaluating and reporting LET and variable RBE in a guideline for the three Dutch proton therapy centers, providing clarity for future clinical interpretation. Having chosen a single variable RBE model offers practicality, although its accuracy remains a topic of ongoing research.
Authors
- Mirko Unipan (ORCID: https://orcid.org/0000-0003-4965-290X)
- Stefan Both (ORCID: https://orcid.org/0000-0001-6652-6054)
- Miranda C.A. Kramer (ORCID: https://orcid.org/0009-0003-5040-998X)
- Steven Habraken (ORCID: https://orcid.org/0009-0002-1168-3479)
- Daniëlle B. P. Eekers (ORCID: https://orcid.org/0000-0003-1917-6279)
- Dik C. van Gent (ORCID: https://orcid.org/0000-0003-1473-8148)
- Hiska L. van der Weide (ORCID: https://orcid.org/0000-0001-6734-2345)
- Ilaria Rinaldi (ORCID: https://orcid.org/0000-0002-2857-0852)
- Inge Compter (ORCID: https://orcid.org/0000-0002-6155-1565)
- Mischa S. Hoogeman (ORCID: https://orcid.org/0000-0002-4264-9903)
- Lara Barazzuol (ORCID: https://orcid.org/0000-0002-6538-2383)
- Jaap Jaspers (ORCID: https://orcid.org/0000-0002-1904-4914)
- Jaap Zindler (ORCID: https://orcid.org/0000-0002-3084-4568)
- Ida E.M. Coremans
- Dirk Wagenaar (ORCID: https://orcid.org/0000-0001-8321-6824)
- Alejandra Méndèz Romero
- Yvonne L.B. Klaver
- D. Scandurra
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- GGD Haaglanden (NL)
- Erasmus MC Cancer Institute (NL)
- Maastro Clinic (NL)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.radonc.2024.110653
- Citations
- 6
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 2.51