Nicotinamide mononucleotide improves the ovarian reserve of POI by inhibiting NLRP3-mediated pyroptosis of ovarian granulosa cells
NMN improves CTX-induced POI by inhibiting NLRP3-mediated pyroptosis, providing a new therapeutic strategy and drug target for clinical POI patients.
Authors
- Xiaocan Lei (ORCID: https://orcid.org/0000-0001-7666-5082)
- Ou Zhong
- Xi Chen (ORCID: https://orcid.org/0000-0002-4224-2556)
- Yue Ma (ORCID: https://orcid.org/0000-0002-6904-3450)
- Weihua Nong
- Ke Liu (ORCID: https://orcid.org/0000-0003-1952-8481)
- Siyuan Lei (ORCID: https://orcid.org/0000-0002-0105-5527)
- Chen Wang (ORCID: https://orcid.org/0009-0004-4302-2565)
Institutions
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- University of South China (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s13048-024-01534-w
- Citations
- 12
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 6.52
Funders
- National Natural Science Foundation of China
- Foundation for Innovative Research Groups of the National Natural Science Foundation of China