Leveraging CAR macrophages targeting c-Met for precision immunotherapy in pancreatic cancer: insights from single-cell multi-omics
CAR macrophages targeting c-Met represent a promising therapeutic strategy for pancreatic cancer, offering targeted elimination of CSCs and disruption of tumor angiogenesis. This study highlights the potential of single-cell multi-omics in guiding the development of precision immunotherapies.
Authors
- Bin Wu (ORCID: https://orcid.org/0000-0002-6696-7471)
- Zhengwei Song (ORCID: https://orcid.org/0000-0002-5557-2298)
- Xiaoguang Wang (ORCID: https://orcid.org/0000-0002-7598-1902)
- Fei Chen (ORCID: https://orcid.org/0000-0002-1679-9932)
- Lingyu Hu
Institutions
- Jiaxing University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s10020-024-00996-4
- Citations
- 9
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.54