Plant Extracts Provide Antiosteoporotic Effect in Vitro

Osteoporosis – is a metabolic chronic disease, that affect bone structure, mineralization and density. It creates a high economic and social burden on society, as it leads to frequent fractures and disability of patients. Among the existing methods and drugs for treatment, none of them provides a complete cure for osteoporosis, but only maintains the bone tissue of the body from further destruction. The plant extracts are considered as biological supplements that prevent the development of osteoporosis at early stages, when the use of more serious drugs can only harm the body. The developed plant extracts increase the production of bone collagen and enhance its mineralization with calcium salts, as well as reduce the number of lytic enzymes that contribute to bone destruction. Thus, having a dual effect against osteoporosis, plant extracts may prove to be a promising drug for further in vivo research.

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Published
2024-09-30
DOI
https://doi.org/10.1109/sibircon63777.2024.10758539
Primary Topic
Cynara cardunculus studies
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article
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article

Plant Extracts Provide Antiosteoporotic Effect in Vitro

Natalya A. Bondarenko, Natalya A.Slazhneva, Alina V.Bahareva
Cynara cardunculus studies
article

Plant Extracts Provide Antiosteoporotic Effect in Vitro

Natalya A. Bondarenko, Natalya A.Slazhneva, Alina V.Bahareva
article en

Abstract

Osteoporosis – is a metabolic chronic disease, that affect bone structure, mineralization and density. It creates a high economic and social burden on society, as it leads to frequent fractures and disability of patients. Among the existing methods and drugs for treatment, none of them provides a complete cure for osteoporosis, but only maintains the bone tissue of the body from further destruction. The plant extracts are considered as biological supplements that prevent the development of osteoporosis at early stages, when the use of more serious drugs can only harm the body. The developed plant extracts increase the production of bone collagen and enhance its mineralization with calcium salts, as well as reduce the number of lytic enzymes that contribute to bone destruction. Thus, having a dual effect against osteoporosis, plant extracts may prove to be a promising drug for further in vivo research.

Russian Academy of Sciences (RU), Novosibirsk State Agricultural University (RU), Institute of Cytology and Genetics (RU), Siberian Branch of the Russian Academy of Sciences (RU), Institute of Clinical and Experimental Lymphology (RU)
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Cynara cardunculus studies
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Plant Extracts Provide Antiosteoporotic Effect in Vitro — Natalya A. Bondarenko, Natalya A.Slazhneva, et al. · (2024) | TGRS Research Map | TGRS