Epidemiology of healthcare-associated bloodstream infection in South African neonatal units
Most HA-BSI events affected preterm neonates at the central hospital with onsite surgery. One-third of patients with HA-BSI died, with highest mortality in preterm infants and Gram-negative/fungal BSI. Empiric antibiotic regimens provide moderate coverage of circulating pathogens but require annual review given increasing carbapenem resistance rates.
Authors
- Andrew Whitelaw (ORCID: https://orcid.org/0000-0001-9070-5247)
- Adrie Bekker (ORCID: https://orcid.org/0000-0003-3836-3432)
- Natasha Raygaan Rhoda (ORCID: https://orcid.org/0000-0002-9194-5522)
- Cari van Schalkwyk (ORCID: https://orcid.org/0000-0001-5154-1390)
- Larisse Bolton (ORCID: https://orcid.org/0000-0001-7879-2173)
- Mark Wates
- C. J. Geldenhuys (ORCID: https://orcid.org/0000-0003-3593-5247)
- Nancy Connell (ORCID: https://orcid.org/0000-0003-0489-3777)
- Aaqilah Fataar (ORCID: https://orcid.org/0000-0003-2280-132X)
- Angela Dramowski (ORCID: https://orcid.org/0000-0002-0161-9791)
- Kessendri Reddy (ORCID: https://orcid.org/0000-0002-6701-9764)
- Arnoldus Engelbrecht (ORCID: https://orcid.org/0009-0003-5740-1745)
- Damien Roux (ORCID: https://orcid.org/0000-0002-6103-6416)
- Marlize Kunneke
- Lloyd Tooke (ORCID: https://orcid.org/0000-0001-5905-9996)
- Thandi Wessels
- Louisa Erasmus
Institutions
- Western Cape Department of Health (ZA)
- University of Cape Town (ZA)
- Stellenbosch University (ZA)
- Somerset Hospital (ZA)
- Groote Schuur Hospital (ZA)
- South African Heart Association (ZA)
- Karl Bremer Hospital (ZA)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s12879-024-10219-0
- Citations
- 1
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- National Research Foundation
- National Health Laboratory Service
- National Institutes of Health
- Fogarty International Center