Increased Rate of Unique Mitochondrial DNA Deletion Breakpoints in Young Adults With Early-Life Stress
The increased number of unique mtDNA deletion breakpoints in participants with ELS suggests that mitochondrial genomes undergo observable alterations in the context of early stress. Future studies will examine mtDNA deletions with metabolic health measures.
Authors
- Audrey A. Omidsalar (ORCID: https://orcid.org/0000-0002-5070-1417)
- Brandi Rollins (ORCID: https://orcid.org/0000-0002-1332-1263)
- Audrey R. Tyrka
- Marquis P. Vawter (ORCID: https://orcid.org/0000-0002-7987-6309)
- Eric W. Smith
- Teresa E. Daniels (ORCID: https://orcid.org/0000-0002-7826-1556)
- Anna Sherman (ORCID: https://orcid.org/0000-0002-0058-7054)
- Brooke E. Hjelm (ORCID: https://orcid.org/0000-0001-8234-2343)
- Stephanie H. Parade (ORCID: https://orcid.org/0000-0003-0978-0886)
- William W. Lewis-de los Angeles (ORCID: https://orcid.org/0000-0003-3858-2299)
Institutions
- University of Southern California (US)
- Providence College (US)
- University of California, Irvine (US)
- Brown University (US)
- Bradley Hospital (US)
- Butler Hospital (US)
- Hasbro Children's Hospital (US)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.bpsgos.2024.100422
- Citations
- 2
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Niagara University
- National Institute on Aging
- National Institute of Mental Health
- National Institute of General Medical Sciences
- Eunice Kennedy Shriver National Institute of Child Health and Human Development