Continuous tremor monitoring in Parkinson’s disease: A wristwatch-inspired triboelectric sensor approach
Parkinson's disease (PD) prevalence is projected to reach 12 million by 2040. Wearable sensors offer a promising approach for comfortable, continuous tremor monitoring to optimize treatment strategies. Here, we present a wristwatch-like triboelectric sensor (WW-TES) inspired by automatic watches for unobtrusive PD tremor assessment. The WW-TES utilizes a free-standing design with a surface-modified polytetrafluoroethylene (PTFE) film and a stainless-steel rotor within a biocompatible polylactic acid (PLA) package. Electrode distance is optimized to maximize the output signal. We propose and discuss the WW-TES working mechanism. The final design is validated for activities of daily living (ADLs), with varying signal amplitudes corresponding to tremor severity levels ("normal" to "severe") based on MDS-UPDRS tremor frequency. Wavelet packet transform (WPT) is employed for signal analysis during ADLs. The WW-TES demonstrates the potential for continuous tremor monitoring, offering an accurate screening of severity and comfortable, unobtrusive wearability.
Authors
- Thitirat Charoonsuk (ORCID: https://orcid.org/0000-0002-9027-9556)
- Swati Panda (ORCID: https://orcid.org/0000-0002-4367-6452)
- Satana Pongampai (ORCID: https://orcid.org/0000-0003-1163-583X)
- Sugato Hajra (ORCID: https://orcid.org/0000-0002-2049-4509)
- Naratip Vittayakorn (ORCID: https://orcid.org/0000-0001-9245-0639)
- Basanta K. Panigrahi (ORCID: https://orcid.org/0000-0002-1761-7643)
- Hoe Joon Kim (ORCID: https://orcid.org/0000-0003-1180-7830)
- Sirinya Ukasi
Institutions
- Siksha O Anusandhan University (IN)
- Daegu Gyeongbuk Institute of Science and Technology (KR)
- King Mongkut's University of Technology Thonburi (TH)
- Srinakharinwirot University (TH)
- King Mongkut's Institute of Technology Ladkrabang (TH)
Publication Details
- Journal
- iScience
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.isci.2024.111480
- Citations
- 13
- Primary Topic
- Advanced Sensor and Energy Harvesting Materials
- Type
- article
- Field-Weighted Citation Impact
- 2.40
Funders
- Srinakharinwirot University
- National Research Foundation
- Ministry of Trade, Industry and Energy
- National Research Foundation of Korea
- Srinakharinwirot University
- Ministry of Higher Education, Science, Research and Innovation, Thailand
- Thailand Science Research and Innovation
- Thailand Institute of Nuclear Technology