Four-year secukinumab treatment outcomes in European real-world patients with axial spondyloarthritis and psoriatic arthritis
This large European real-world study demonstrates that 4-year secukinumab retention rates were approximately 50% in both axSpA and PsA. b/tsDMARD naïve patients had higher retention, remission and LDA rates than patients with prior b/tsDMARD exposure.
Authors
- Sanne Høj Christensen
- Stylianos Georgiadis (ORCID: https://orcid.org/0000-0003-3485-9457)
- Johan K. Wallman (ORCID: https://orcid.org/0000-0002-4915-2924)
- Anna‐Mari Hokkanen (ORCID: https://orcid.org/0000-0001-5448-5080)
- Florenzo Iannone (ORCID: https://orcid.org/0000-0003-0474-5344)
- Adrian Ciurea (ORCID: https://orcid.org/0000-0002-7870-7132)
- Irene van der Horst‐Bruinsma (ORCID: https://orcid.org/0000-0002-8086-9915)
- Jakub Závada (ORCID: https://orcid.org/0000-0002-9802-6545)
- Brigitte Michelsen (ORCID: https://orcid.org/0000-0003-0103-2840)
- Miguel Bernardes (ORCID: https://orcid.org/0000-0002-1849-5465)
- Karin Laas
- Anne Gitte Loft (ORCID: https://orcid.org/0000-0001-6374-841X)
- Katja Perdan Pirkmajer (ORCID: https://orcid.org/0000-0001-7778-4016)
- Michael John Nissen (ORCID: https://orcid.org/0000-0002-6326-1764)
- Lykke Midtbøll Ørnbjerg (ORCID: https://orcid.org/0000-0002-7832-6831)
- Fernando Sánchez‐Alonso (ORCID: https://orcid.org/0009-0000-1189-2380)
- Gary J. Macfarlane (ORCID: https://orcid.org/0000-0003-2322-3314)
- Paweł Mielnik (ORCID: https://orcid.org/0000-0002-3894-5371)
- Ólafur Pálsson (ORCID: https://orcid.org/0000-0001-5295-2183)
- Dan Nordström
- Gareth T. Jones (ORCID: https://orcid.org/0000-0003-0016-7591)
- Björn Guðbjörnsson (ORCID: https://orcid.org/0000-0003-4631-6505)
- Isabel Castrejón (ORCID: https://orcid.org/0000-0003-1811-2417)
- Merete Lund Hetland (ORCID: https://orcid.org/0000-0003-4229-6818)
- Mikkel Østergaard (ORCID: https://orcid.org/0000-0003-3690-467X)
- J. Heberg (ORCID: https://orcid.org/0000-0001-6129-9235)
- Sigrid Vorobjov (ORCID: https://orcid.org/0009-0006-0248-6026)
- Fatoş Önen (ORCID: https://orcid.org/0000-0002-6341-2622)
- Nikita Khmelinskii (ORCID: https://orcid.org/0000-0001-6358-7388)
- Bente Glintborg (ORCID: https://orcid.org/0000-0002-8931-8482)
- Žiga Rotar (ORCID: https://orcid.org/0000-0002-9323-9189)
- Karel Pavelká (ORCID: https://orcid.org/0000-0003-1952-8422)
- Z. Faizy Ahmadzay
- Simon Horskjær Rasmussen (ORCID: https://orcid.org/0000-0001-6928-277X)
- Marion Pons (ORCID: https://orcid.org/0000-0001-6531-9846)
- Cătălin Codreanu (ORCID: https://orcid.org/0000-0001-6600-9946)
Institutions
- Radboud University Nijmegen (NL)
- Lund University (SE)
- Dokuz Eylül University (TR)
- University of Aberdeen (GB)
- University of Zurich (CH)
- Helsinki University Hospital (FI)
- Glostrup Hospital (DK)
- Aarhus University Hospital (DK)
- Rigshospitalet (DK)
- Radboud University Medical Center (NL)
- Institute of Rheumatology (CZ)
- East Tallinn Central Hospital (EE)
- University Hospital of Zurich (CH)
- University Hospital of Geneva (CH)
- Skåne University Hospital (SE)
- Spanish Society of Hematology and Hemotherapy (ES)
- National Institute for Health Development (EE)
- Helse Førde (NO)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Joint Bone Spine
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.jbspin.2024.105824
- Citations
- 4
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Novartis
- Novartis Pharma