Effects of dupilumab on mannitol airway hyperresponsiveness in uncontrolled severe asthma
Dupilumab attenuated mannitol AHR to a clinically relevant degree despite concomitant inhaled corticosteroid reduction, combined with improvements in lung function, asthma control, and quality of life.
Authors
- Rory Chan (ORCID: https://orcid.org/0000-0003-2805-8266)
- Chris RuiWen Kuo (ORCID: https://orcid.org/0000-0001-5954-6620)
- Brian J. Lipworth (ORCID: https://orcid.org/0000-0002-8140-2014)
- Kirsten Stewart (ORCID: https://orcid.org/0000-0002-2799-9868)
Institutions
- University of Dundee (GB)
- Ninewells Hospital (GB)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.jaci.2024.11.024
- Citations
- 14
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.57
Funders
- Sanofi
- University of Dundee
- Sanofi Genzyme