Distinct therapeutic effects of auraptene and umbelliprenin on TNF-α and IL-17 levels in a murine model of chronic inflammation
AUR and UMB regulate TNF-α and IL-17 differently; AUR inhibits both, showing broad therapeutic potential, while UMB specifically targets TNF-α, showing a specialized role.
Authors
- Amin Reza Nikpoor (ORCID: https://orcid.org/0000-0001-5619-8771)
- Vahid Reza Askari (ORCID: https://orcid.org/0000-0001-9268-6270)
- Mehrdad Iranshahi (ORCID: https://orcid.org/0000-0002-3018-5750)
- Fatemeh Yarmohammadi (ORCID: https://orcid.org/0000-0002-0552-8766)
- Armin Attaranzadeh (ORCID: https://orcid.org/0000-0002-6903-0465)
- Leila Etemad (ORCID: https://orcid.org/0000-0002-2800-9395)
- Zhila Taherzadeh (ORCID: https://orcid.org/0000-0001-7185-970X)
- Saeid Joveini
Institutions
- Mashhad University of Medical Sciences (IR)
- Kermanshah University of Medical Sciences (IR)
- Biotechnology Research Center (IR)
- Hormozgan University of Medical Sciences (IR)
Publication Details
- Journal
- Heliyon
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e40731
- Citations
- 4
- Primary Topic
- Plant chemical constituents analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.40
Funders
- Mashhad University of Medical Sciences