Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer
This study highlights the relatively uniform adipocyte size across fat depots in patients with metastatic breast cancer, with potential changes in mammary adipocytes over the disease course. The microscopic tumor cell infiltration observed in the visceral fat, mainly for ILC, underscores the need to undertake additional research to understanding the contribution of the adipose tissue in breast cancer metastasis.
Authors
- Ha-Linh Nguyen (ORCID: https://orcid.org/0000-0002-2538-7657)
- Hava Izci (ORCID: https://orcid.org/0000-0002-3344-0198)
- Kristien Borremans (ORCID: https://orcid.org/0000-0001-7047-1543)
- Marion Maetens (ORCID: https://orcid.org/0000-0002-0505-2622)
- Anirudh Pabba (ORCID: https://orcid.org/0000-0003-2002-6956)
- Amena Mahdami (ORCID: https://orcid.org/0000-0002-3226-6933)
- Josephine Van Cauwenberge (ORCID: https://orcid.org/0000-0001-9802-186X)
- Sophia Leduc (ORCID: https://orcid.org/0000-0002-4931-1999)
- François Richard (ORCID: https://orcid.org/0000-0003-4353-3619)
- Christine Desmedt (ORCID: https://orcid.org/0000-0002-5223-5579)
- Maxim De Schepper (ORCID: https://orcid.org/0000-0001-9829-8535)
- Hans Wildiers (ORCID: https://orcid.org/0000-0001-8990-7837)
- Karen Van Baelen (ORCID: https://orcid.org/0000-0002-5700-3574)
- Gitte Zels (ORCID: https://orcid.org/0000-0002-6332-3830)
- Tatjana Geukens (ORCID: https://orcid.org/0000-0001-8828-8739)
- Giuseppe Floris (ORCID: https://orcid.org/0000-0003-2391-5425)
- Wouter Van Den Bogaert (ORCID: https://orcid.org/0000-0002-5803-3409)
- Sigrid Hatse (ORCID: https://orcid.org/0000-0002-6764-2628)
- Patrick Neven
Institutions
- KU Leuven (BE)
Publication Details
- Journal
- The Breast
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1016/j.breast.2024.103852
- Citations
- 2
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- KU Leuven
- Fondation contre le Cancer