Identification of fungal pathogens among COVID-19 and non COVID-19 cases in Bhaktapur hospital, Nepal
The prevalence of fungal pathogens among COVID-positive and negative cases was 6.70% and 22.77% respectively. In COVID positive cases, Candida albicans (33.33%) was predominantly followed by Aspergillus flavus 2(22.22%) and Candida tropicalis, Mucor spp. and Aspergillus fumigatus. In COVID negative cases, Candida albicans (69.60%) prevailed followed by Trichosporon spp., Candida parapsilosis, Mucor and Alternaria. Age and gender were not associated with fungal infection. Most Candida spp. were susceptible to miconazole but resistant to ketoconazole. To the best of our knowledge, this study represents the first report from Nepal on critical and high priority fungal pathogens categorized by WHO. With fungal infections on the rise, enhanced clinical vigilanceand antifungal susceptibility testing are warranted.
Authors
- Srijana Koirala
- Suprina Sharma (ORCID: https://orcid.org/0000-0002-6402-6934)
- Sunil Regmi (ORCID: https://orcid.org/0000-0003-1338-8748)
- Krishna Gurung
- Kaveri Pandit
- Jyoti Acharya (ORCID: https://orcid.org/0000-0002-0235-8538)
- Jiwan Thapa (ORCID: https://orcid.org/0000-0001-6616-9595)
- Supriya Sharma (ORCID: https://orcid.org/0000-0002-3183-0483)
- Sanjib Adhikari (ORCID: https://orcid.org/0000-0002-5874-2547)
- Shreedhar Aryal (ORCID: https://orcid.org/0000-0003-2879-698X)
- Asmita Lamichhane (ORCID: https://orcid.org/0009-0006-2966-6836)
- Sweety Upadhaya
- Pramod Poudel
Institutions
- Pokhara University (NP)
- Tribhuvan University (NP)
- National Public Health Laboratory (NP)
- Western Regional Hospital (NP)
- Bhaktapur Cancer Hospital (NP)
Publication Details
- Journal
- BMC Research Notes
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1186/s13104-024-07010-4
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tribhuvan University
- University Grants Commission
- University Grants Commission- Nepal