Association of systemic immune-inflammation index with all-cause and cardio-cerebrovascular mortality in individuals with diabetic kidney disease: evidence from NHANES 1999-2018
Increased SII levels, whether examined as continuous variables or categorized, demonstrate a significant association with elevated risks of all-cause and cardio-cerebrovascular disease mortality among DKD patients. These findings imply that maintaining SII within an optimal range could be crucial in reducing mortality risk.
Authors
- Manhuai Zhang (ORCID: https://orcid.org/0009-0000-7451-0036)
- Sixiu Chen
- Huajing Peng
- Kam Wa Chan (ORCID: https://orcid.org/0000-0002-3175-1574)
- Meng Zhang (ORCID: https://orcid.org/0000-0001-7436-0402)
- Siyang Ye (ORCID: https://orcid.org/0009-0001-4973-5476)
- Qiong Wen (ORCID: https://orcid.org/0000-0002-0517-8460)
- Suchun Li (ORCID: https://orcid.org/0000-0002-5748-681X)
- Бин Ли (ORCID: https://orcid.org/0000-0002-8038-0140)
- Yiqin Wang (ORCID: https://orcid.org/0000-0001-7806-992X)
- Wei Chen (ORCID: https://orcid.org/0000-0001-5649-081X)
- Sydney C.W. Tang (ORCID: https://orcid.org/0000-0002-6862-1941)
- Peng Xie (ORCID: https://orcid.org/0000-0001-9017-1679)
- Li Tan (ORCID: https://orcid.org/0000-0003-4987-5118)
- Jianbo Li
Institutions
- Hong Kong Baptist University (HK)
- Sun Yat-sen University (CN)
- Chinese University of Hong Kong (HK)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3389/fendo.2024.1399832
- Citations
- 4
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Natural Science Foundation of Guangdong Province
- Centers for Disease Control and Prevention