Anti‐fibrotic effects of lisinopril ( <scp>ACE</scp> inhibitor) and fasudil ( <scp>ROCK</scp> inhibitor) in combination for canine corneal fibrosis in vitro
An ophthalmic formulation consisting of lisinopril and fasudil may offer a safe and effective method to treat canine corneal fibrosis. Additional studies evaluating safety and efficacy of this formulation in vivo are warranted.
Authors
- Elizabeth A. Giuliano (ORCID: https://orcid.org/0000-0002-9874-8935)
- Brayden L. Routh (ORCID: https://orcid.org/0000-0003-2045-2023)
- Prashant R. Sinha
- Rajiv R. Mohan (ORCID: https://orcid.org/0000-0002-1857-4200)
- Ratnakar Tripathi (ORCID: https://orcid.org/0000-0002-7398-8115)
- Payton Lujin
Institutions
- University of Missouri Health System (US)
- Harry S. Truman Memorial Veterans' Hospital (US)
- Cincinnati Eye Institute (US)
- University of Missouri (US)
Publication Details
- Journal
- Veterinary Ophthalmology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1111/vop.13304
- Citations
- 2
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- ACVO Vision for Animals Foundation