Distinct clinical characteristics of adolescent idiopathic scoliosis with asymmetrical <scp>ESR1</scp> expression in paraspinal muscle progenitor cells
There were 48% of AIS patients with significantly decreased ESR1 expression in concave paraspinal muscle progenitor cells (convex/concave>1.5 folds), while patients with more asymmetrical ESR1 expression showed more hypoplastic paraspinal muscle and fatty infiltration on the concave side, and more severe scoliotic deformity.
Authors
- Wenyuan Sui (ORCID: https://orcid.org/0009-0001-8538-9339)
- Hanlong Xin
- Xiexiang Shao (ORCID: https://orcid.org/0000-0003-4837-1305)
- Junlin Yang (ORCID: https://orcid.org/0000-0002-9050-4039)
- Wenhua Mao
Institutions
- Shanghai Jiao Tong University (CN)
- Wenzhou Medical University (CN)
- XinHua Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- JOR Spine
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1002/jsp2.70018
- Citations
- 1
- Primary Topic
- Scoliosis diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Natural Science Foundation of China