Increased specificity of the “GFAP/UCH-L1” mTBI rule-out test by age dependent cut-offs
The "GFAP/UCH-L1" mTBI test is an efficient "rule-out test" to exclude patients suffering from mTBI. By adjusting the cut-offs in patients older than 65 years old, we could significantly increase the number of CT head scans avoided without affecting the sensitivity. These new cut-offs should be externally validated.
Authors
- Aurélie Ladang (ORCID: https://orcid.org/0000-0002-5316-3108)
- Konstantinos Makris (ORCID: https://orcid.org/0000-0002-7896-9028)
- Athanasios C. Mitrοpoulos (ORCID: https://orcid.org/0000-0002-7962-8153)
- Konstantinos Vlachos (ORCID: https://orcid.org/0000-0003-2794-1065)
- Étienne Cavalier (ORCID: https://orcid.org/0000-0003-0947-2226)
- Ioulia Trifonidi (ORCID: https://orcid.org/0000-0002-3999-8459)
- Georgios Vavoulis
- Katerina Karagianni
- Emma Calluy
Institutions
- University of Liège (BE)
- KAT General Hospital of Attica (GR)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1515/cclm-2024-1034
- Citations
- 8
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 2.95