Synthesis of Dibenzoxasilepine Using Ring Expansion Reaction of a Pentacoordinate Silicon Intermediate
Abstract Dibenzoxasilepine is an important skeleton in both synthetic organic and medicinal chemistry. Here, we have succeeded in obtaining it in higher yield than the conventional method, elucidating for the first time the rearrangement tendency of the two aromatic rings during the ring expansion reaction on the cyclic pentacoordinate silicon intermediate.
Authors
- Mitsuhiro Arisawa (ORCID: https://orcid.org/0000-0002-7937-670X)
- Tsunayoshi Takehara (ORCID: https://orcid.org/0000-0002-4113-7578)
- Makoto Sako (ORCID: https://orcid.org/0000-0002-4268-7002)
- Keigo Watanabe
- Tsuyoshi Matsuzaki
- Takeyuki Suzuki (ORCID: https://orcid.org/0000-0002-2137-0276)
- M. Sato (ORCID: https://orcid.org/0009-0003-7687-4660)
- Kaori Asano
Institutions
- Osaka Research Institute of Industrial Science and Technology (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Advanced Synthesis & Catalysis
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1002/adsc.202401125
- Citations
- 1
- Primary Topic
- Chemical Synthesis and Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.25