Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma

Based on the predictive model developed in this study, BLCA patients' prognoses can be accurately predicted. SB505124 could become an important drug in the treatment of BLCA patients. RAC3 is essential in prognosis, immune microenvironment, and malignant behavior of BLCA <i>in vitro</i> and <i>in vivo</i>. It will also offer the potential for personalized treatment for BLCA patients and generate new research avenues for clinical investigators.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2024-11-26
DOI
https://doi.org/10.3389/fphar.2024.1503623
Citations
1
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.42
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article

Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma

Shiwei Huang, Jing Tan, Zhun Zhang, Yusong Zhou et al.
1 citations
Frontiers in Pharmacology
Ferroptosis and cancer prognosis
0.42
article

Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma

Shiwei Huang, Jing Tan, Zhun Zhang, Yusong Zhou, Bing Yang, Wei Liu
article en
1 citations

Abstract

Based on the predictive model developed in this study, BLCA patients' prognoses can be accurately predicted. SB505124 could become an important drug in the treatment of BLCA patients. RAC3 is essential in prognosis, immune microenvironment, and malignant behavior of BLCA <i>in vitro</i> and <i>in vivo</i>. It will also offer the potential for personalized treatment for BLCA patients and generate new research avenues for clinical investigators.

Frontiers in PharmacologyVol. 15
Central South University (CN), Zunyi Medical University (CN), Third Xiangya Hospital (CN)
Good health and well-being
Openalex Percentile: Top 30%
Ferroptosis and cancer prognosis
0.42
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