Role of anoikis-related gene RAC3 in prognosis, immune microenvironment, and contribution to malignant behavior in vitro and in vivo of bladder urothelial carcinoma
Based on the predictive model developed in this study, BLCA patients' prognoses can be accurately predicted. SB505124 could become an important drug in the treatment of BLCA patients. RAC3 is essential in prognosis, immune microenvironment, and malignant behavior of BLCA <i>in vitro</i> and <i>in vivo</i>. It will also offer the potential for personalized treatment for BLCA patients and generate new research avenues for clinical investigators.
Authors
- Shiwei Huang
- Jing Tan (ORCID: https://orcid.org/0000-0002-1099-1544)
- Zhun Zhang (ORCID: https://orcid.org/0009-0001-8218-5277)
- Yusong Zhou
- Bing Yang (ORCID: https://orcid.org/0000-0001-6183-8163)
- Wei Liu (ORCID: https://orcid.org/0000-0002-4935-7591)
Institutions
- Central South University (CN)
- Zunyi Medical University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3389/fphar.2024.1503623
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.42