Comprehensive prognostic gene identification and functional characterization of GRAMD1A in Wilms tumor: development of risk prediction models and therapeutic implications
This study identifies novel prognostic genes and potential therapeutic targets in WT. GRAMD1A, SPR, EBAG9, RBM47, and RIDA play critical roles in WT progression, with GRAMD1A as a key oncogenic factor, offering potential for risk stratification and future therapeutic intervention.
Authors
- Mingxian Xu (ORCID: https://orcid.org/0000-0003-4580-7804)
- Yong Zeng (ORCID: https://orcid.org/0000-0001-6995-8960)
- Linshan Zeng (ORCID: https://orcid.org/0009-0004-3542-7079)
- Qiang Zeng (ORCID: https://orcid.org/0000-0002-2759-422X)
- Zhong Liu (ORCID: https://orcid.org/0000-0002-5747-3146)
- Lilu Qin
- Junfeng Tao
Institutions
- Sun Yat-sen University (CN)
- Jiangxi Maternal and Child Health Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3389/fonc.2024.1501718
- Citations
- 2
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Education Department of Jiangxi Province