DNA methylation patterns of circadian and ultradian genes are altered in the peripheral blood of patients with hidradenitis suppurativa
Altered DNA methylation patterns of genes related to circadian and ultradian pathways could contribute to immune system derangement and inflammatory processes chronicization in addition to other comorbidities hallmarking HS onset and progression, at the same time representing possible druggable targets.
Authors
- Lavanya V. Uppala (ORCID: https://orcid.org/0000-0002-5459-4217)
- Devendrasinh Jhala (ORCID: https://orcid.org/0000-0002-1339-6492)
- Giovanni Damiani (ORCID: https://orcid.org/0000-0002-2390-6505)
- Uppala Ratnamala (ORCID: https://orcid.org/0000-0002-5972-7437)
- Gianluigi Mazzoccoli (ORCID: https://orcid.org/0000-0003-3535-7635)
- Uppala Radhakrishna (ORCID: https://orcid.org/0000-0002-6617-5634)
- Rakesh Rawal (ORCID: https://orcid.org/0000-0002-7985-1187)
- Aaren Vedangi (ORCID: https://orcid.org/0000-0003-3175-1520)
- Maulikkumar Patel (ORCID: https://orcid.org/0000-0003-3914-2797)
- Nazia Saiyed
- Tommaso Mazza (ORCID: https://orcid.org/0000-0003-0434-8533)
- Gregor B. E. Jemec (ORCID: https://orcid.org/0000-0002-0712-2540)
- Sushma R. Shah
Institutions
- Gujarat University (IN)
- University of Nebraska at Omaha (US)
- University of Pittsburgh (US)
- University of Milan (IT)
- Zealand University Hospital (DK)
- B.J. Medical College (IN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3389/fimmu.2024.1475424
- Citations
- 4
- Primary Topic
- Hidradenitis Suppurativa and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.14