Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice
Aerobic exercise enhances memory and learning abilities, improves cognitive function, and reduces the oxidative stress levels in the hippocampus of AD mice, which involves in the activation of Keap1/Nrf2/GPX4 pathway.
Authors
- Zhenzhen Gao (ORCID: https://orcid.org/0000-0002-9518-7634)
- Guoyuan Pan (ORCID: https://orcid.org/0000-0002-3231-7446)
- Ye Bo Zhou (ORCID: https://orcid.org/0000-0002-0273-007X)
- Yucheng Wu (ORCID: https://orcid.org/0000-0002-0348-9206)
- Shiyan Wang (ORCID: https://orcid.org/0000-0002-8240-7933)
- Yajun Mao
- Yvonne Lang
Institutions
- Zhejiang Chinese Medical University (CN)
- Tongde Hospital of Zhejiang Province (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3389/fnins.2024.1505650
- Citations
- 7
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Zhejiang Chinese Medical University