snRNA-seq of human ovaries reveals heat shock proteins are associated with obesity related cancer risk
Our study identified a cluster of genes in ovarian cells that are suppressed by obesity, including those belonging to HSP family genes. These findings provide valuable insights for investigating the link between obesity and ovarian diseases.
Authors
- Shigang Zhao (ORCID: https://orcid.org/0000-0002-7407-9220)
- Yonghui Jiang (ORCID: https://orcid.org/0000-0003-1996-8954)
- Xueqi Yan (ORCID: https://orcid.org/0000-0003-0799-6624)
- Ziyi Yang (ORCID: https://orcid.org/0000-0001-5883-9552)
- Xueying Gao (ORCID: https://orcid.org/0000-0002-5868-5378)
- Yunhai Yu (ORCID: https://orcid.org/0000-0002-4511-8999)
- Zhenguo Zhao (ORCID: https://orcid.org/0000-0003-1230-3116)
- Gengchen Feng
- Shumin Li (ORCID: https://orcid.org/0000-0001-8083-1071)
- Yuhan Zhang (ORCID: https://orcid.org/0000-0002-6001-0062)
- Yimeng Li (ORCID: https://orcid.org/0009-0002-2170-2442)
- Weihan Zhang (ORCID: https://orcid.org/0000-0002-9498-8245)
- Zi‐Jiang Chen (ORCID: https://orcid.org/0000-0001-6637-6631)
- Han Zhao (ORCID: https://orcid.org/0000-0002-7197-0333)
Institutions
- Shandong University (CN)
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Renji Hospital (CN)
- Second Hospital of Shandong University (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s12967-024-05898-x
- Citations
- 4
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- National Key Research and Development Program of China