“Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine”

Despite high variability in cellularity, the concentration of MSCs correlated strongly with BMC cellularity, suggesting that total cell counts can be used to estimate MSC numbers in BMCs. However, cellularity is not an indicator of a particularly high MSC content. This study supports the use of cell counts as a measure for estimating MSC concentration in BMCs. Future research should focus on establishing direct comparisons with other BMC products and exploring factors influencing cellularity and MSC percentages to enhance BMC quality for clinical applications.

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Publication Details

Journal
Bone Reports
Published
2024-11-26
DOI
https://doi.org/10.1016/j.bonr.2024.101820
Citations
1
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
0.44
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article

“Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine”

Klaus Werner Labarre, G. Zimmermann, Peter Ansgar Grathwol
1 citations
Bone Reports
Mesenchymal stem cell research
0.44
article

“Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine”

Klaus Werner Labarre, G. Zimmermann, Peter Ansgar Grathwol
article en
1 citations

Abstract

Despite high variability in cellularity, the concentration of MSCs correlated strongly with BMC cellularity, suggesting that total cell counts can be used to estimate MSC numbers in BMCs. However, cellularity is not an indicator of a particularly high MSC content. This study supports the use of cell counts as a measure for estimating MSC concentration in BMCs. Future research should focus on establishing direct comparisons with other BMC products and exploring factors influencing cellularity and MSC percentages to enhance BMC quality for clinical applications.

Bone ReportsVol. 24
Marienkrankenhaus Hamburg (DE)
Zero hunger
Openalex Percentile: Top 30%
Mesenchymal stem cell research
0.44
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