“Cellularity as a predictive tool for mesenchymal stem cell concentration in bone marrow concentrates: Implications for regenerative medicine”
Despite high variability in cellularity, the concentration of MSCs correlated strongly with BMC cellularity, suggesting that total cell counts can be used to estimate MSC numbers in BMCs. However, cellularity is not an indicator of a particularly high MSC content. This study supports the use of cell counts as a measure for estimating MSC concentration in BMCs. Future research should focus on establishing direct comparisons with other BMC products and exploring factors influencing cellularity and MSC percentages to enhance BMC quality for clinical applications.
Authors
- Klaus Werner Labarre
- G. Zimmermann
- Peter Ansgar Grathwol
Institutions
- Marienkrankenhaus Hamburg (DE)
Publication Details
- Journal
- Bone Reports
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.bonr.2024.101820
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.44