Combined diet and exercise training decreases serum lipids associated with insulin resistance
These data show that serum sphingolipid species previously linked to insulin resistance in humans can be reduced with insulin-sensitizing lifestyle interventions. Furthermore, individuals with elevated serum TAG may significantly benefit from lifestyle interventions that increase insulin sensitivity due to a greater decrease in serum lipids related to insulin resistance.
Authors
- Joseph T. Brozinick (ORCID: https://orcid.org/0000-0002-7946-3432)
- Leigh Perreault (ORCID: https://orcid.org/0000-0002-1481-7535)
- Anna A. Kerege
- Karin Zemski Berry
- Josiane L. Broussard (ORCID: https://orcid.org/0000-0002-6824-8294)
- Sean A. Newsom (ORCID: https://orcid.org/0000-0003-0585-3830)
- Darcy Kahn (ORCID: https://orcid.org/0000-0002-3764-1202)
- Amanda Garfield (ORCID: https://orcid.org/0009-0006-1449-4939)
- Bryan C. Bergman (ORCID: https://orcid.org/0000-0002-9561-1052)
- Simona Zarini (ORCID: https://orcid.org/0000-0002-7460-3299)
- Hai H. Bui
Institutions
- Oregon State University (US)
- Eli Lilly (United States) (US)
- University of Colorado Anschutz Medical Campus (US)
- Colorado State University (US)
Publication Details
- Journal
- Obesity
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1002/oby.24156
- Citations
- 6
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- American Diabetes Association
- National Institutes of Health