A transcriptomic comparison of in vitro models of the human placenta
None of the models were a close approximation of the human bulk placental transcriptome, highlighting the challenges with model selection. To enable appropriate model selection, we adapted our data into a web application: "Comparative Transcriptomic Placental Model Atlas (CTPMA)".
Authors
- Sheela Sathyanarayana (ORCID: https://orcid.org/0000-0002-1480-0397)
- Leena Kadam (ORCID: https://orcid.org/0000-0002-1812-5210)
- James A. Litch (ORCID: https://orcid.org/0000-0003-0570-0308)
- Alison G. Paquette (ORCID: https://orcid.org/0000-0002-6065-9398)
- Leslie Myatt (ORCID: https://orcid.org/0000-0002-2569-7807)
- Evan J. Firsick (ORCID: https://orcid.org/0000-0001-9171-126X)
- Samantha Lapehn (ORCID: https://orcid.org/0000-0001-6299-7633)
- Sylvie Girard (ORCID: https://orcid.org/0000-0002-5164-5816)
- Bhagwat Prasad (ORCID: https://orcid.org/0000-0002-9090-0912)
- James W. MacDonald (ORCID: https://orcid.org/0000-0002-7328-7626)
- Nicole R. Bush (ORCID: https://orcid.org/0000-0003-0217-9975)
- Ciara Thoreson
- S.K. Nair
Institutions
- Center for Infectious Disease Research (US)
- Seattle Children's Hospital (US)
- Oregon Health & Science University (US)
- Washington State University Spokane (US)
- University of California, San Francisco (US)
- University of Washington (US)
- Seattle Children's Hospital (US)
- Mayo Clinic in Arizona (US)
- Global Alliance to Prevent Prematurity and Stillbirth (US)
Publication Details
- Journal
- Placenta
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.placenta.2024.11.007
- Citations
- 11
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.41
Funders
- University of Washington
- Urban Child Institute
- National Institutes of Health
- National Institute of Environmental Health Sciences