Circulating necroptosis markers in chronic pancreatitis and pancreatic cancer: Associations with diagnosis and prognostic factors
Circulating levels of MLKL are lower in patients with CP than PDAC. Elevated sST2 levels are associated with pancreatic diseases. Further studies are required to show whether MLKL and sST2 could be useful biomarkers in evaluating pancreatic diseases.
Authors
- Hanna Belfrage (ORCID: https://orcid.org/0000-0003-4121-223X)
- Krista Kuuliala (ORCID: https://orcid.org/0000-0002-3586-5712)
- Antti Kuuliala (ORCID: https://orcid.org/0000-0002-3190-207X)
- Pauli Puolakkainen (ORCID: https://orcid.org/0000-0003-2489-4371)
- Hanna Seppänen (ORCID: https://orcid.org/0000-0002-2529-651X)
- Johanna Louhimo (ORCID: https://orcid.org/0000-0002-6208-978X)
- Harri Mustonen (ORCID: https://orcid.org/0000-0001-5632-6796)
- Leena Kylänpää
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Hospital District of Helsinki and Uusimaa (FI)
Publication Details
- Journal
- Pancreatology
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1016/j.pan.2024.11.016
- Citations
- 4
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.94