Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder
At present, it remains to be understood whether initiating the treatment prenatally, or prolonging the duration of treatment will be necessary in order to achieve similar results in vivo in CDD mice to those obtained in vitro.
Authors
- Giorgio Medici (ORCID: https://orcid.org/0000-0002-8531-3887)
- Marianna Tassinari (ORCID: https://orcid.org/0000-0003-2078-9638)
- Beatrice Uguagliati (ORCID: https://orcid.org/0000-0001-7944-5368)
- Stefania Trazzi (ORCID: https://orcid.org/0000-0003-2623-2769)
- Nicola Mottolese (ORCID: https://orcid.org/0000-0002-3066-0945)
- Elisabetta Ciani (ORCID: https://orcid.org/0000-0003-3130-5168)
- Manuela Loi (ORCID: https://orcid.org/0000-0002-6179-7610)
- Giulia Candini
- Khalid Iqbal (ORCID: https://orcid.org/0000-0002-7670-9580)
Institutions
- New York State Office for People With Developmental Disabilities (US)
- 490 BioTech (United States) (US)
- University of Bologna (IT)
Publication Details
- Journal
- Journal of Neurodevelopmental Disorders
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s11689-024-09583-4
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00