RNA Sequencing and Weighted Gene Co-Expression Network Analysis Highlight DNA Replication and Key Genes in Nucleolin-Depleted Hepatoblastoma Cells

Our findings demonstrate the functional consequences of nucleolin depletion in HepG2 and confirm the importance of nucleolin in DNA replication and cell cycle processes. These data will further enhance our understanding of the molecular and pathologic mechanisms of nucleolin and provide new therapeutic perspectives in disease.

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Publication Details

Journal
Genes
Published
2024-11-26
DOI
https://doi.org/10.3390/genes15121514
Citations
3
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.70
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article

RNA Sequencing and Weighted Gene Co-Expression Network Analysis Highlight DNA Replication and Key Genes in Nucleolin-Depleted Hepatoblastoma Cells

Markus Schosserer, Victoria Sarne, Hannes Steinkellner, Silvia Madritsch et al.
3 citations
Genes
RNA modifications and cancer
0.70
article

RNA Sequencing and Weighted Gene Co-Expression Network Analysis Highlight DNA Replication and Key Genes in Nucleolin-Depleted Hepatoblastoma Cells

Markus Schosserer, Victoria Sarne, Hannes Steinkellner, Silvia Madritsch, Winfried Neuhaus, Franco Laccone, Anna Huber, Raimund Oberle, Alexander V. Beribisky, Teresa Seipel, Manfred Kluge
article en
3 citations

Abstract

Our findings demonstrate the functional consequences of nucleolin depletion in HepG2 and confirm the importance of nucleolin in DNA replication and cell cycle processes. These data will further enhance our understanding of the molecular and pathologic mechanisms of nucleolin and provide new therapeutic perspectives in disease.

GenesVol. 15(12)
Danube Private University (AT), University of Vienna (AT), AIT Austrian Institute of Technology GmbH (AT), Medical University of Vienna (AT)
Good health and well-being
Openalex Percentile: Top 29%
RNA modifications and cancer
0.70
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