Safety and evidence base of a combined oral contraceptive based on estherol and drospirenone: a brief summary

Family planning is a fundamental concept for building and development of society in the 21st century. The beliefs that developed over the last century and the priorities that changed resulted in the ecological and reproductive dissonance, the main consequences of which are the increasing age at first birth, decreasing total fertility rate, and increasing incidence of gynecological diseases. Hormonal contraception is one of the main family planning methods, which makes it possible to build up reserves for women’s reproductive health preservation and effectively control reproductive function. In turn, combined oral contraceptives (COCs) represent the most convenient method. Recently, an innovative estetrol/drospirenone-based COC, which, according to a number of studies, is among the most versatile and favorable in terms of extracontraceptive benefits, went on sale in the Russian Federation. In this regard, it is necessary to analyze the available data and create a concise summary of the proven advantages of this COC in the context of a number of characteristics.