Rare case of hypothyroidism in a child

Hypothyroidism is a decrease or complete loss of thyroid function. In childhood, congenital hypothyroidism is the most common, which can be either permanent or transient. One of the reasons for the development of hypothyroidism in newborns may be the mother's intake of large doses of iodine during pregnancy and, as a consequence, the occurrence of the Wolf–Chaikoff phenomenon to prevent the synthesis of large amounts of thyroid hormones by the thyroid gland of the fetus and newborn. We present a clinical observation of a rare form of hypothyroidism with goiter in a child born to a mother who took narcotic drugs containing large doses of iodine. In the presented observation, hypothyroidism was transient in nature; a feature of the disease was a long-lasting enlargement of the thyroid gland. Taking into account that even a temporary decrease in the level of thyroid hormones can negatively affect the neuropsychic development of the child, the newborn patient was prescribed replacement therapy with levothyroxine sodium at a dose of 25 mcg/day. The patient's long-standing goiter served as the reason for prolonging replacement therapy until the age of 1 year and subsequent resumption of therapy twice until the volume of the thyroid gland normalized.

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Publication Details

Journal
Clinical review for general practice
Published
2024-09-26
DOI
https://doi.org/10.47407/kr2024.5.9.00481
Primary Topic
Thyroid Disorders and Treatments
Type
article
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article

Rare case of hypothyroidism in a child

Tatyana V. Kovalenko, Irina Petrova, Liaisan M. Mullakhmetova
Clinical review for general practice
Thyroid Disorders and Treatments
article

Rare case of hypothyroidism in a child

Tatyana V. Kovalenko, Irina Petrova, Liaisan M. Mullakhmetova
article en

Abstract

Hypothyroidism is a decrease or complete loss of thyroid function. In childhood, congenital hypothyroidism is the most common, which can be either permanent or transient. One of the reasons for the development of hypothyroidism in newborns may be the mother's intake of large doses of iodine during pregnancy and, as a consequence, the occurrence of the Wolf–Chaikoff phenomenon to prevent the synthesis of large amounts of thyroid hormones by the thyroid gland of the fetus and newborn. We present a clinical observation of a rare form of hypothyroidism with goiter in a child born to a mother who took narcotic drugs containing large doses of iodine. In the presented observation, hypothyroidism was transient in nature; a feature of the disease was a long-lasting enlargement of the thyroid gland. Taking into account that even a temporary decrease in the level of thyroid hormones can negatively affect the neuropsychic development of the child, the newborn patient was prescribed replacement therapy with levothyroxine sodium at a dose of 25 mcg/day. The patient's long-standing goiter served as the reason for prolonging replacement therapy until the age of 1 year and subsequent resumption of therapy twice until the volume of the thyroid gland normalized.

Clinical review for general practiceVol. 5(9)
Good health and well-being
Openalex Percentile: Top 66%
Thyroid Disorders and Treatments
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Rare case of hypothyroidism in a child — Tatyana V. Kovalenko, Irina Petrova, et al. · Clinical review for general practice (2024) | TGRS Research Map | TGRS