Advancements in wearable heart sounds devices for the monitoring of cardiovascular diseases

Abstract Cardiovascular diseases remain a leading global cause of mortality, underscoring the urgent need for intelligent diagnostic tools to enhance early detection, prediction, diagnosis, prevention, treatment, and recovery. This demand has spurred the advancement of wearable and flexible technologies, revolutionizing continuous, noninvasive, and remote heart sound (HS) monitoring—a vital avenue for assessing heart activity. The conventional stethoscope, used to listen to HSs, has limitations in terms of its physical structure, as it is inflexible and bulky, which restricts its prospective applications. Recently, mechanoacoustic sensors have made remarkable advancements, evolving from primitive forms to soft, flexible, and wearable designs. This article provides an in‐depth review of the latest scientific and technological advancements by addressing various topics, including different types of sensors, sensing materials, design principles, denoising techniques, and clinical applications of flexible and wearable HS sensors. This transformative potential lies in the capacity for ongoing, remote, and personalized monitoring, promising enhanced patient outcomes, amplified remote monitoring capabilities, and timely diagnoses. Last, the article highlights current challenges and prospects for the future, suggesting techniques to advance HS sensing technologies for exciting real‐time applications.