Design and synthesis of camphor‐thiazole derivatives as potent antifungal agents: structure–activity relationship and preliminary mechanistic study
In this study, the designed and optimized compound C5 emerged as a promising candidate for potent antifungal agents. The results demonstrate that synthesized camphor-thiazole derivatives possess potent antifungal activity and can serve as lead compounds for further optimization in antifungal agent development. © 2024 Society of Chemical Industry.
Authors
- Yu‐Cheng Gu (ORCID: https://orcid.org/0000-0002-6400-6167)
- Yafang Sun
- Yanan Dang (ORCID: https://orcid.org/0000-0002-0283-2797)
- Peng Dai (ORCID: https://orcid.org/0000-0003-0663-8016)
- Weihua Zhang (ORCID: https://orcid.org/0000-0003-1994-5306)
- Huizhen Xue
- Jiaxuan Huang
- Zihua Ma
- Qing Xia
Institutions
- Nanjing Agricultural University (CN)
- Huaibei Normal University (CN)
- Syngenta (United Kingdom) (GB)
Publication Details
- Journal
- Pest Management Science
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1002/ps.8563
- Citations
- 2
- Primary Topic
- Fungal Plant Pathogen Control
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities