Shared Genetic Links Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease

Our results show that there are significant gene overlaps and pleiotropic genes between NAFLD and CAD and point out their common molecular mechanisms. These findings provide evidence for the common etiology between them and also help to better understand the pleiotropic nature between NAFLD and CAD, which may be of guiding significance for future treatment strategies.

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Publication Details

Journal
Global Heart
Published
2024-11-26
DOI
https://doi.org/10.5334/gh.1374
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Shared Genetic Links Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease

Chengan Xu, Keyang Xu, Qiao qiao Yin, Shouhao Wang et al.
Global Heart
Liver Disease Diagnosis and Treatment
article

Shared Genetic Links Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease

Chengan Xu, Keyang Xu, Qiao qiao Yin, Shouhao Wang, Wei Zheng, Hua Di
article en

Abstract

Our results show that there are significant gene overlaps and pleiotropic genes between NAFLD and CAD and point out their common molecular mechanisms. These findings provide evidence for the common etiology between them and also help to better understand the pleiotropic nature between NAFLD and CAD, which may be of guiding significance for future treatment strategies.

Global HeartVol. 19(1)
Hong Kong Baptist University (HK), Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN), Hangzhou Medical College (CN)
Good health and well-being
Openalex Percentile: Top 68%
Liver Disease Diagnosis and Treatment
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