Application of the Sponge Model Implants in the Study of Vaccine Memory in Mice Previously Immunized with LBSap
The findings emphasized the impact of genetic background on the populations engaged in immune responses, suggesting that this model can be utilized to enhance and track both innate and adaptive immune responses in vaccine candidates. Consequently, these results may inform the selection of the most suitable experimental model for biomolecule testing, taking into account how the unique characteristics of each mouse strain affect the immune response dynamics.
Authors
- Mariana Ferreira Lanna
- Walderez O. Dutra (ORCID: https://orcid.org/0000-0002-7586-9996)
- Denise Silveira-Lemos (ORCID: https://orcid.org/0000-0003-0955-458X)
- Érika Michalsky Monteiro (ORCID: https://orcid.org/0000-0002-6224-3417)
- Kenneth J. Gollob (ORCID: https://orcid.org/0000-0003-4184-3867)
- Olindo Assis Martins‐Filho (ORCID: https://orcid.org/0000-0002-5494-4889)
- Lucilene Aparecida Resende
- Sandra Aparecida Lima de Moura (ORCID: https://orcid.org/0000-0002-3406-0437)
- Wanessa Goes (ORCID: https://orcid.org/0000-0002-1323-432X)
- Edelberto Santos Dias (ORCID: https://orcid.org/0000-0002-2370-5113)
- Rodolfo Cordeiro Giunchetti (ORCID: https://orcid.org/0000-0003-4181-7546)
- Paula Mello De Luca (ORCID: https://orcid.org/0000-0002-2017-8602)
- Alexandre Barbosa Reis (ORCID: https://orcid.org/0000-0001-8123-4164)
- André Tetzl Costa (ORCID: https://orcid.org/0000-0002-1621-8085)
- Maykelin Fuentes Zaldívar (ORCID: https://orcid.org/0000-0002-6419-4479)
Institutions
- Universidade Federal de Ouro Preto (BR)
- Universidade Federal de Minas Gerais (BR)
- Hospital Israelita Albert Einstein (BR)
- Universidade José do Rosário Vellano (BR)
- Hospital São Paulo (BR)
- Fundação Oswaldo Cruz (BR)
- Insper (BR)
Publication Details
- Journal
- Vaccines
- Published
- 2024-11-26
- DOI
- https://doi.org/10.3390/vaccines12121322
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00