Longitudinal history of mammographic breast density and breast cancer risk by familial risk, menopausal status, and initial mammographic density level in a high risk cohort: a nested case–control study
Women who maintain higher levels of mammographic density (i.e. do not decrease over time) or have increasing mammographic density over time have a higher risk of subsequent breast cancer than women with high mammographic density that decreases over time. These findings suggest potential for incorporating mammographic density trajectories in clinical risk assessment, and the importance of additional breast cancer monitoring in women not experiencing declines in mammographic density over time.
Authors
- Parisa Tehranifar (ORCID: https://orcid.org/0000-0002-0605-3934)
- Ying Wei (ORCID: https://orcid.org/0000-0002-7164-8109)
- Dale P. Sandler (ORCID: https://orcid.org/0000-0002-6776-0018)
- Mary Beth Terry (ORCID: https://orcid.org/0000-0002-4106-5033)
- Alexandra J. White (ORCID: https://orcid.org/0000-0003-2455-2945)
- Shweta Athilat
- Erica Lee (ORCID: https://orcid.org/0000-0002-7045-2673)
- Katie M. O’Brien
- Yuyan Liao
Institutions
- Columbia University Irving Medical Center (US)
- National Institute of Environmental Health Sciences (US)
- Columbia University (US)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s13058-024-01917-3
- Citations
- 4
- Primary Topic
- Digital Radiography and Breast Imaging
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- National Institutes of Health
- National Cancer Institute
- National Institute of Environmental Health Sciences