An immune scoring system predicts prognosis and immune characteristics in lung adenocarcinoma brain metastases by RNA sequencing
We identified two immune-related subtypes which used to estimate prognosis and immune characteristics and developed a reliable GYMS-related risk signature in LUAD BrMs. These results will enhance the understanding of the immune microenvironment in LUAD BrMs and lay the theoretical foundation for the development of personalized therapies for LUAD patients with BrMs.
Authors
- Guilong Tanzhu (ORCID: https://orcid.org/0000-0002-7948-0662)
- Lifeng Li (ORCID: https://orcid.org/0000-0002-9813-5688)
- Rongrong Zhou (ORCID: https://orcid.org/0000-0003-4483-0615)
- Xuan Gao (ORCID: https://orcid.org/0000-0003-0448-2206)
- Zhiyuan Liu (ORCID: https://orcid.org/0000-0001-9738-2719)
- Xuefeng Xia (ORCID: https://orcid.org/0000-0002-4419-1158)
- Gang Xiao (ORCID: https://orcid.org/0000-0003-0299-5681)
Institutions
- Central South University (CN)
- Chinese Academy of Sciences (CN)
- Microbiology Institute of Shaanxi (CN)
- Institute of Microbiology (CN)
- China National GeneBank (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Acta Neuropathologica Communications
- Published
- 2024-11-26
- DOI
- https://doi.org/10.1186/s40478-024-01895-9
- Citations
- 5
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- CIEE Ping Foundation