Impact of Revised Diagnostic Testing Algorithms and Case Definitions on Lyme Disease Surveillance in a Low-Incidence State: An Interrupted Time Series Analysis
We evaluated the impact of the endorsement of modified 2-tiered testing and its inclusion in updated Lyme disease case definitions in North Carolina using surveillance data from 2017-2023. After the implementation of modified 2-tiered testing, confirmed cases increased by 117%, with comparable decreases in probable cases compared with prior periods.
Authors
- Carl J. Williams (ORCID: https://orcid.org/0000-0003-4274-3227)
- Dana Giandomenico
- Brandon Hollingsworth (ORCID: https://orcid.org/0000-0002-1772-8191)
- Gayoung Lee (ORCID: https://orcid.org/0009-0003-9300-0359)
- Teresa G. Fisher
- Ross M. Boyce (ORCID: https://orcid.org/0000-0002-9489-6324)
Institutions
- University of North Carolina at Chapel Hill (US)
- NC Department of Health and Human Services (US)
- Cornell University (US)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1093/cid/ciae545
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of North Carolina