Chimeric peptides targeting the receptor-binding domain of SARS-CoV-2 variants inhibit ACE2 interaction

The chimeric Trx-RB9 and Trx-RB10 peptides bind to the RBD of SARS-CoV-2 variants and inhibit the binding of ACE2 to the RBD of the Omicron trimeric S.

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Publication Details

Journal
Asian Pacific Journal of Allergy and Immunology
Published
2024-12-01
DOI
https://doi.org/10.12932/ap-030424-1833
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Chimeric peptides targeting the receptor-binding domain of SARS-CoV-2 variants inhibit ACE2 interaction

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Chimeric peptides targeting the receptor-binding domain of SARS-CoV-2 variants inhibit ACE2 interaction

Jiraporn Panmanee, Surapon Piboonpocanun, Ittipat Meewan, Jukrapun Komaikul, Promsin Masrinoul, Pisit Ubonsri
article en

Abstract

The chimeric Trx-RB9 and Trx-RB10 peptides bind to the RBD of SARS-CoV-2 variants and inhibit the binding of ACE2 to the RBD of the Omicron trimeric S.

Asian Pacific Journal of Allergy and ImmunologyVol. 43(1)
Mahidol University (TH)
Mahidol University, National Research Council of Thailand
Good health and well-being
Openalex Percentile: Top 73%
SARS-CoV-2 and COVID-19 Research
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