Annexin A1, calreticulin and high mobility group box 1 are elevated in secondary progressive multiple sclerosis: Does immunogenic cell death occur in multiple sclerosis?
Although further studies are suggested in this regard, this data could imply induction of ICD in MS. The proposed ICD might trigger immune response against neural cells resulting in neuroinflammation and demyelination in CNS in MS. Our observation could suggest inclusion of ICD interfering treatments in routine MS therapy.
Authors
- Ommoleila Molavi (ORCID: https://orcid.org/0000-0002-1820-7048)
- Soheila Montazersaheb (ORCID: https://orcid.org/0000-0001-5010-7293)
- Mohammad Saeid Hejazi (ORCID: https://orcid.org/0000-0002-1033-3998)
- Sevda Jafari
- Masoud Nikanfar (ORCID: https://orcid.org/0000-0002-1409-7611)
- Vahid Hosseini (ORCID: https://orcid.org/0000-0002-1307-0564)
- Mahnaz Talebi
Institutions
- Tabriz University of Medical Sciences (IR)
- Razi Hospital (IR)
Publication Details
- Journal
- Bioimpacts
- Published
- 2024-09-08
- DOI
- https://doi.org/10.34172/bi.30264
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tabriz University of Medical Sciences
- University of Tabriz