<scp>USP5</scp>‐dependent <scp>HDAC1</scp> promotes cisplatin resistance and the malignant progression of non–small cell lung cancer by regulating <scp>RILP</scp> acetylation levels
USP5-dependentstabilization of HDAC1 contributed to cisplatin resistance and the malignancy of NSCLC by diminishing the levels of RILP acetylation, which suggested that targeting the HDAC1-USP5axis might represent a novel therapeutic strategy for overcoming DDP resistance in NSCLC patients.
Authors
- Yulin Jin (ORCID: https://orcid.org/0000-0002-7142-5589)
- Mingfeng Zheng
- Rongguo Lu
Institutions
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2024-11-24
- DOI
- https://doi.org/10.1111/1759-7714.15478
- Citations
- 4
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.94