Analytical Validation and Performance Evaluation of Amplicon-Based Next-Generation Sequencing Assays for Detecting ERBB2 and Other Gene Amplifications in Solid Tumors
This study highlights the strengths and limitations of amplicon-based NGS assays in detecting amplifications using real-world data.
Authors
- Anna Plotkin
- Kenneth J. Craddock (ORCID: https://orcid.org/0000-0001-9702-0830)
- Sharon Nofech‐Mozes (ORCID: https://orcid.org/0000-0001-5450-9986)
- Weei-Yuarn Huang (ORCID: https://orcid.org/0009-0001-3604-9645)
- Hong Wang (ORCID: https://orcid.org/0000-0001-6649-649X)
- Danny Chan (ORCID: https://orcid.org/0000-0003-1456-7844)
- Rashmi S. Goswami (ORCID: https://orcid.org/0000-0001-6037-5582)
- Ekaterina Olkhov‐Mitsel (ORCID: https://orcid.org/0000-0001-7945-7801)
- August Lin
- David Hwang (ORCID: https://orcid.org/0000-0003-0831-6053)
- G D Luk
Institutions
- Western University (CA)
- Sunnybrook Health Science Centre (CA)
- University of Toronto (CA)
- North York General Hospital (CA)
- Health Sciences Centre (CA)
- Sunnybrook Research Institute
Publication Details
- Journal
- Cancers
- Published
- 2024-11-23
- DOI
- https://doi.org/10.3390/cancers16233927
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.29