The Impact of the Dialysis Event Prevention Bundle on the Reduction in Dialysis Event Rate in Patients with Catheters: A Retrospective and Prospective Cohort Study

<b>Background:</b> Dialysis-associated events such as bloodstream infections represent serious complications for hemodialysis patients, with the potential to increase morbidity and mortality. <b>Aims:</b> To assess the impact of implementing a comprehensive bundle of evidence-based practice on reducing dialysis event rates among catheter dialysis patients at Prince Mansour Military Hospital Dialysis Center. <b>Participants and Methods:</b> The study enrolled 111 hemodialysis participants. A comprehensive dialysis event prevention bundle consisting of 6 key components was implemented. <b>Results:</b> Implementation of the dialysis event prevention bundle showed a significant decrease in IV antimicrobial start (<i>p</i> = 0.003), positive blood culture (<i>p</i> = 0.039), and inflammation at the vascular access site eliminated (<i>p</i> = 0.004). There was a positive correlation between IV antimicrobial start and both patients' age (<i>p</i> = 0.005) and the permanent catheter site (<i>p</i> = 0.002). Positive blood culture was significantly correlated with comorbidities (<i>p</i> = 0.000) and patients' age (<i>p</i> = 0.320). A positive correlation between pus, redness, or increased swelling at the vascular access site with comorbidities (<i>p</i> = 0.034), patients' age (<i>p</i> = 0.021), and the permanent catheter site (<i>p</i> = 0.002) was observed. Staff compliance with the dialysis event prevention bundle components has improved regarding hemodialysis catheter disconnection, catheter exit site care, and routine disinfection. <b>Conclusions:</b> Implementation of a comprehensive dialysis event prevention bundle can effectively reduce dialysis event rates and enhance patient safety.